Endoplasmic reticulum tubules limit the size of misfolded protein condensates
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DOI: 10.7554/elife.71642
Abstract: The endoplasmic reticulum (ER) is composed of sheets and tubules. Here we report that the COPII coat subunit, SEC24C, works with the long form of the tubular ER-phagy receptor, RTN3, to target dominant-interfering mutant proinsulin… read more here.
Keywords: endoplasmic reticulum; reticulum tubules; puncta; akita puncta ... See more keywords