Calcium dobesilate prevents the oxidative stress and inflammation induced by diabetes in the retina of db/db mice.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of diabetes and its complications"
DOI: 10.1016/j.jdiacomp.2017.07.009
Abstract: AIM Calcium dobesilate (CaD) is beneficial in early stages of diabetic retinopathy (DR), but its mechanisms of action remains to be elucidated. The aim was to investigate the effect of CaD on proinflammatory cytokines and… read more here.
Keywords: calcium dobesilate; cad; retina mice; induced diabetes ... See more keywords
Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2021.05.04
Abstract: AIM To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes. METHODS In experiments in vitro, stimulation by chemical hypoxia was established in ARPE-19 cells. Then, the expression of hypoxia-inducible… read more here.
Keywords: hif vegfa; piperine retina; expression; retina mice ... See more keywords
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.811897
Abstract: Diabetic retinopathy (DR) is a complication of diabetes that has a serious impact on the quality of life of patients. VEGFA is necessary in the physiological state to maintain endothelial activity and physical properties of… read more here.
Keywords: reduces vascular; signaling pathway; dioscin reduces; vascular damage ... See more keywords