An Engineering Platform for Clinical Application of Optogenetic Therapy in Retinal Degenerative Diseases
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Journal of Translational Engineering in Health and Medicine"
DOI: 10.1109/jtehm.2023.3275103
Abstract: Optogenetics is a new approach for controlling neural circuits with numerous applications in both basic and clinical science. In retinal degenerative diseases, the photoreceptors die, but inner retinal cells remain largely intact. By expressing light… read more here.
Keywords: degenerative diseases; retinal degenerative; engineering platform; therapy ... See more keywords
Intraretinal pigmented cells in retinal degenerative disease
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Ophthalmology"
DOI: 10.1136/bjophthalmol-2021-320392
Abstract: Purpose Invasion of pigmented cells into the retina occurs in retinal degenerative diseases, such as macular telangiectasia type 2 (MacTel) and retinitis pigmentosa (RP). These intraretinal pigmented cells may be derived from the retinal pigment… read more here.
Keywords: retinal degenerative; degenerative disease; rpe cells; pigmented cells ... See more keywords
Contribution of Interleukin-17A to Retinal Degenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.847937
Abstract: Retinal degenerative diseases are a leading cause of vision loss and blindness throughout the world, characterized by chronic and progressive loss of neurons and/or myelin. One of the common features of retinal degenerative diseases and… read more here.
Keywords: degenerative diseases; retinal degenerative; interleukin 17a; 17a retinal ... See more keywords
Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23062918
Abstract: Purpose: The lack of suitable animal models for (dry) age-related macular degeneration (AMD) has hampered therapeutic research into the disease, so far. In this study, pigmented rats and mice were systematically injected with various doses… read more here.
Keywords: injection; iodate injection; sodium iodate; retinal degenerative ... See more keywords
Sigma-1 Receptor in Retina: Neuroprotective Effects and Potential Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147572
Abstract: Retinal degenerative diseases are the major factors leading to severe visual impairment and even irreversible blindness worldwide. The therapeutic approach for retinal degenerative diseases is one extremely urgent and hot spot in science research. The… read more here.
Keywords: degenerative diseases; retinal degenerative; neuroprotective effects; receptor retina ... See more keywords
Topical Treatment for Retinal Degenerative Pathologies: A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098045
Abstract: The topical administration of medicines is the preferred route in ocular therapy, at least for the anterior segment of the eye. However, the eye’s inherent functional and biological barriers all work against the active pharmaceutical… read more here.
Keywords: retinal degenerative; treatment retinal; topical treatment; systematic review ... See more keywords
Polyphenols and Visual Health: Potential Effects on Degenerative Retinal Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26113407
Abstract: Dietary polyphenols are a group of natural compounds that have been proposed to have beneficial effects on human health. They were first known for their antioxidant properties, but several studies over the years have shown… read more here.
Keywords: degenerative diseases; retinal diseases; visual health; potential effects ... See more keywords
Inflammation and retinal degenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.350192
Abstract: Vision is an ability that depends on the precise structure and functioning of the retina. Any kind of stress or injury can disrupt the retinal architecture and leads to vision impairment, vision loss, and blindness.… read more here.
Keywords: degenerative diseases; retinal degenerative; inflammation retinal; vision ... See more keywords