Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.11.004
Abstract: Polycomb repressive complexes maintain transcriptional repression of genes encoding crucial developmental regulators through chromatin modification. Here we investigated the role of Polycomb repressive complex 2 (PRC2) in retinal development by inactivating its key components Eed… read more here.
Keywords: retinal differentiation; polycomb; progenitor cells; retinal progenitor ... See more keywords
Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells translational medicine"
DOI: 10.1093/stcltm/szad028
Abstract: Prior to use, newly generated induced pluripotent stem cells (iPSC) should be thoroughly validated. While excellent validation and release testing assays designed to evaluate potency, genetic integrity, and sterility exist, they do not have the… read more here.
Keywords: cell; retinal differentiation; capacity; propensity ... See more keywords