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Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12637
Abstract: Rhodopsin is the visual pigment that mediates dim‐light vision in vertebrates and is a model system for the study of retinal disease. The majority of rhodopsin experiments are performed using bovine rhodopsin; however, recent evidence…
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Keywords:
bovine rhodopsin;
retinal disease;
rhodopsin;
experimental comparison ... See more keywords
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Published in 2017 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2017.01.006
Abstract: Mutations in the gene BEST1 are causally associated with as many as five clinically distinct retinal degenerative diseases, which are collectively referred to as the "bestrophinopathies". These five associated diseases are: Best vitelliform macular dystrophy,…
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Keywords:
bestrophin retinal;
best1;
macular dystrophy;
retinal disease ... See more keywords
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Published in 2018 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2018.1448060
Abstract: ABSTRACT Introduction: Pharmacotherapy with visual cycle modulators (VCMs) is under investigation for retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardt macular dystrophy (SMD) and nonexudative age-related macular degeneration (AMD), all blinding diseases that lack effective…
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Keywords:
vcms;
pharmacotherapy retinal;
retinal disease;
visual cycle ... See more keywords
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Published in 2022 at "Retina"
DOI: 10.1097/iae.0000000000003571
Abstract: PURPOSE To provide a concise review of induced pluripotent stem cells (iPSCs) and retinal organoids (ROs) as models for human retinal diseases and their role in gene discovery and treatment of inherited retinal diseases (IRDs).…
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Keywords:
models human;
pluripotent stem;
retinal disease;
disease ... See more keywords
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Published in 2023 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000000948
Abstract: Purpose of review Intravitreal and periocular injections for retinal disease provide a targeted delivery of medication to the eye. However, given risks of injections, including endophthalmitis, pain and treatment burden for both patients and retina…
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Keywords:
retinal disease;
disease;
oral medications;
management retinal ... See more keywords
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Published in 2020 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000883
Abstract: Purpose of review Retinal disease can manifest with visual symptoms similar to those which result from central nervous system disorders. We provide a framework for considering retinal causes of common visual complaints presenting to a…
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Keywords:
retinal disease;
disease neurology;
neurology clinic;
visual complaints ... See more keywords
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Published in 2022 at "Cellular and Molecular Life Sciences"
DOI: 10.1101/2022.02.07.479069
Abstract: Inherited retinal diseases (IRDs) are a heterogeneous group of blinding disorders, which result in dysfunction or death of the light-sensing cone and rod photoreceptors. Despite individual IRDs (Inherited retinal disease) being rare, collectively, they affect…
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Keywords:
cone;
retinal disease;
survival;
inherited retinal ... See more keywords
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Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3178372
Abstract: In recent years, there has been an unprecedented growth in computer vision and deep learning implementation owing to the exponential rise of computation infrastructure. The same was also reflected in retinal image analysis and successful…
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Keywords:
learning strategies;
retinal disease;
learning;
fundus images ... See more keywords
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Published in 2022 at "IEEE Transactions on Medical Imaging"
DOI: 10.1109/tmi.2022.3155154
Abstract: There are many types of retinal disease, and accurately detecting these diseases is crucial for proper diagnosis. Convolutional neural networks (CNNs) typically perform well on detection tasks, and the attention module of CNNs can generate…
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Keywords:
complementary heatmap;
disease detection;
retinal disease;
loss ... See more keywords
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Published in 2018 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13831
Abstract: tive vitreoretinopathy (Mulder et al. 2017). Here, we measured aqueous flare in patients with wAMD, diabetic macular oedema (DME), cystoid macular oedema (CME) due to retinal vein occlusion (RVO) and CME related to other retinal…
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Keywords:
anti vegf;
retinal disease;
aqueous flare;
treatment ... See more keywords
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Published in 2022 at "Acta Ophthalmologica"
DOI: 10.1111/aos.15110
Abstract: Diabetic retinopathy (DR) is a sight‐threatening complication of diabetes mellitus (DM) and it contributes substantially to the burden of disease globally. During the last decades, the development of multiple imaging modalities to evaluate DR, combined…
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Keywords:
imaging diabetic;
imaging modalities;
retinal disease;
disease ... See more keywords