Computer‐aided diagnosis of retinal diseases using multidomain feature fusion
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22379
Abstract: In this article, an attempt is made to combine both transform and spatial domain features to increase the accuracy, sensitivity, and specificity for the classification of retinal diseases. Papilloedema, macular edema, glaucoma, diabetic retinopathy (DR),… read more here.
Keywords: feature; feature fusion; fusion; computer aided ... See more keywords
Modeling Retinal Diseases Using Genetic Approaches in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7720-8_3
Abstract: Genetic mouse models mimicking human diseases have been developed and utilized for retinal research in various topics, involving anatomy, physiology, biochemistry, and pathology. The main reasons why mouse models are important for retinal research include… read more here.
Keywords: mouse models; diseases using; using genetic; modeling retinal ... See more keywords
Role of Curcumin in Retinal Diseases—A review
Sign Up to like & getrecommendations! Published in 2022 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05542-0
Abstract: To review the role of curcumin in retinal diseases, COVID era, modification of the molecule to improve bioavailability and its future scope. PubMed and MEDLINE searches were pertaining to curcumin, properties of curcumin, curcumin in… read more here.
Keywords: role curcumin; retinal diseases; curcumin retinal; review role ... See more keywords
An Introduction to Biosimilars for the Treatment of Retinal Diseases: A Narrative Review
Sign Up to like & getrecommendations! Published in 2022 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-022-00488-w
Abstract: Biological therapies have revolutionized the treatment of disease across a number of therapeutic areas including retinal diseases. However, on occasion, such treatments may be relatively more expensive compared to small molecule therapies. This can restrict… read more here.
Keywords: review; introduction biosimilars; biosimilars treatment; treatment ... See more keywords
Challenges of cost-effectiveness analyses of novel therapeutics for Inherited Retinal Diseases: Cost-effectiveness analysis in Inherited Retinal Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.08.009
Abstract: PURPOSE To discuss the challenges and potential improvement strategies of cost-effectiveness analyses performed for therapeutics targeting inherited retinal diseases. DESIGN Perspective METHODS: : Literature review with discussion of current limitations and improvement recommendations. RESULTS Cost-effectiveness… read more here.
Keywords: inherited retinal; cost; health; cost effectiveness ... See more keywords
Classification of diabetes-related retinal diseases using a deep learning approach in optical coherence tomography
Sign Up to like & getrecommendations! Published in 2019 at "Computer methods and programs in biomedicine"
DOI: 10.1016/j.cmpb.2019.06.016
Abstract: BACKGROUND AND OBJECTIVES Spectral Domain Optical Coherence Tomography (SD-OCT) is a volumetric imaging technique that allows measuring patterns between layers such as small amounts of fluid. Since 2012, automatic medical image analysis performance has steadily… read more here.
Keywords: optical coherence; learning; retinal diseases; coherence tomography ... See more keywords
Recent developments in liposomal drug delivery systems for the treatment of retinal diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.04.004
Abstract: Diseases of the retina cause vision loss and blindness, which have a profound impact on an individual's quality of life. The number of therapies available to treat retinal diseases is limited. Nanoparticle (NP)-based medicines represent… read more here.
Keywords: developments liposomal; drug delivery; delivery systems; drug ... See more keywords
Pharmacotherapy for metabolic and cellular stress in degenerative retinal diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.11.013
Abstract: Retinal photoreceptors continually endure stresses associated with prolonged light exposure and the metabolic demands of dark adaptation. Although healthy photoreceptors are able to withstand these stresses for several decades, the disease-affected retina functions at a… read more here.
Keywords: degenerative retinal; metabolic cellular; cellular stress; pharmacotherapy metabolic ... See more keywords
Progress in treating inherited retinal diseases: Early subretinal gene therapy clinical trials and candidates for future initiatives
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2019.100827
Abstract: Due to improved phenotyping and genetic characterization, the field of 'incurable' and 'blinding' inherited retinal diseases (IRDs) has moved substantially forward. Decades of ascertainment of IRD patient data from Philadelphia and Toronto centers illustrate the… read more here.
Keywords: clinical trials; progress treating; therapy; inherited retinal ... See more keywords
Derivation of three induced pluripotent stem cell lines under feeder-free culture conditions from peripheral blood mononuclear cells (PBMC) of Indian patients suffering from inherited retinal diseases carrying different mutations.
Sign Up to like & getrecommendations! Published in 2020 at "Stem cell research"
DOI: 10.1016/j.scr.2020.101757
Abstract: Inherited retinal diseases (IRDs) are clinically and genetically heterogenous diseases affecting the neural retina and retinal pigment epithelium resulting in irreversible blindness. Owing to advantages like ease of access for treatment, one eye being a… read more here.
Keywords: stem cell; inherited retinal; retinal diseases; induced pluripotent ... See more keywords
G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases
Sign Up to like & getrecommendations! Published in 2017 at "Vision Research"
DOI: 10.1016/j.visres.2017.05.001
Abstract: G protein-coupled receptor 91 (GPR91) is a succinate-specific receptor and activation of GPR91 could initiate a complex signal transduction cascade and upregulate inflammatory and pro-angiogenic cytokines. In the retina, GPR91 is predominately expressed in ganglion… read more here.
Keywords: retinopathy; hypoxic retinal; protein coupled; coupled receptor ... See more keywords