Gene Therapy for Inherited Retinal Disorders: Update on Clinical Trials.
Sign Up to like & getrecommendations! Published in 2021 at "Klinische Monatsblatter fur Augenheilkunde"
DOI: 10.1055/a-1384-0818
Abstract: Within the last decade, continuous advances in molecular biological techniques have made it possible to develop causative therapies for inherited retinal disorders (IRDs). Some of the most promising options are gene-specific approaches using adeno-associated virus-based… read more here.
Keywords: gene therapy; retinal disorders; clinical trials; therapy ... See more keywords
Microscopic Observation of Proliferative Membranes in Fibrocontractive Retinal Disorders
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DOI: 10.1155/2019/9647947
Abstract: Proliferative membranes of fibrocontractive retinal disorders are extensively studied from the morphological and evolutive point of view. Despite this, little is known of their cellular composition. In this study, the authors investigated the morphological characteristics… read more here.
Keywords: membranes fibrocontractive; erm specimens; microscopic observation; fibrocontractive retinal ... See more keywords
Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
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DOI: 10.1371/journal.pone.0254180
Abstract: An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal… read more here.
Keywords: coherence tomography; optical coherence; retinal disorders; diagnosis retinal ... See more keywords
New Insights Into Immunological Therapy for Retinal Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01431
Abstract: In the twentieth century, a conspicuous lack of effective treatment strategies existed for managing several retinal disorders, including age-related macular degeneration; diabetic retinopathy (DR); retinopathy of prematurity (ROP); retinitis pigmentosa (RP); uveitis, including Behçet's disease;… read more here.
Keywords: immunological therapy; treatment strategies; insights immunological; new insights ... See more keywords
Findings from a Genotyping Study of over 1000 People with Inherited Retinal Disorders in Ireland
Sign Up to like & getrecommendations! Published in 2020 at "Genes"
DOI: 10.3390/genes11010105
Abstract: The Irish national registry for inherited retinal degenerations (Target 5000) is a clinical and scientific program to identify individuals in Ireland with inherited retinal disorders and to attempt to ascertain the genetic cause underlying the… read more here.
Keywords: findings genotyping; target capture; genotyping study; inherited retinal ... See more keywords
Recent developments of neuroprotective agents for degenerative retinal disorders
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.335140
Abstract: Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which are caused by a group of retinal diseases affecting various age groups, and increasingly prevalent in… read more here.
Keywords: degeneration; retinal disorders; degenerative retinal; retinal neurons ... See more keywords
Current perspectives on use of anti-vascular endothelial growth factor agents for retinal disorders
Sign Up to like & getrecommendations! Published in 2021 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_72_21
Abstract: The introduction of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) agents has lead to paradigm shifts in management of retinal disorders of various etiologies. We have come a long way from macular photocoagulation for neovascular age‐related… read more here.
Keywords: vascular endothelial; retinal disorders; endothelial growth; growth factor ... See more keywords
Impact of COVID-19-related lockdown on retinal disorders treated with intravitreal injections
Sign Up to like & getrecommendations! Published in 2022 at "Oman Journal of Ophthalmology"
DOI: 10.4103/ojo.ojo_74_21
Abstract: PURPOSE: To study functional changes in vision and morphological changes on optical coherence tomography (OCT) scans in patients where intravitreal therapy (IVT) with injections has been delayed due to COVID-19 pandemic lockdown. METHODS: Retrospective cross-sectional… read more here.
Keywords: impact covid; related lockdown; retinal disorders; covid related ... See more keywords