Parenteral Lipid Dose Restriction With Soy Oil, Not Fish Oil, Preserves Retinal Function in Neonatal Piglets
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Parenteral and Enteral Nutrition"
DOI: 10.1002/jpen.1145
Abstract: BACKGROUND A dietary supply of docosahexaenoic acid (DHA) and arachidonic acid (AA) is critical for neonatal retinal development. Both are absent/minimal in parenteral nutrition (PN) using soy-oil emulsions ([SO] Intralipid®) traditionally used for neonatal intestinal… read more here.
Keywords: retinal function; soy oil; neonatal piglets; fish oil ... See more keywords
Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107797
Abstract: The use of nanomaterials is an emerging therapeutic approach for the treatment of several pathologies. Cerium oxide nanoparticles have been studied for biomedical application, including neurodegenerative disorders, such as age-related macular degeneration in several animal… read more here.
Keywords: focus; neuroprotective effects; function microglia; retinal function ... See more keywords
Using retinal function to define ischemic exclusion criteria for animal models of glaucoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108354
Abstract: Most animal models of glaucoma rely on induction of ocular hypertension (OHT), yet such models can suffer from high IOPs leading to undesirable retinal ischemia. Thus, animals with IOPs exceeding a threshold (e.g. > 60 mmHg) are often… read more here.
Keywords: models glaucoma; retinal function; damage; exclusion criteria ... See more keywords
Improved retinal function in RCS rats after suppressing the over-activation of mGluR5
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03702-z
Abstract: Müller cells maintain retinal synaptic homeostasis by taking up glutamate from the synaptic cleft and transporting glutamine back to the neurons. To study the interaction between Müller cells and photoreceptors, we injected either DL-α-aminoadipate or… read more here.
Keywords: mglur5; retinal function; activation mglur5; improved retinal ... See more keywords
Retinal Function in Patients with Adalimumab Treatment: Long-term Follow-up with Microperimetry
Sign Up to like & getrecommendations! Published in 2019 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2019.1672198
Abstract: ABSTRACT Purpose: To examine the effects of a biological treatment (adalimumab) on visual function in patients with ankylosing spondylitis and in uveitic patients without macular edema during one-year treatment with adalimumab. Methods: Sixteen eyes of… read more here.
Keywords: microperimetry; patients adalimumab; retinal function; treatment ... See more keywords
The Impact of Systemic Medications on Retinal Function.
Sign Up to like & getrecommendations! Published in 2023 at "Asia-Pacific journal of ophthalmology"
DOI: 10.1097/apo.0000000000000605
Abstract: This study will provide a thorough review of systemic (and select intravitreal) medications, along with illicit drugs that are capable of causing various patterns of retinal toxicity. The diagnosis is established by taking a thorough… read more here.
Keywords: impact systemic; impact; kinase; retinal function ... See more keywords
Multimodal imaging analysis for the impact of retinal peripheral lesions on central neurovascular structure and retinal function in type 2 diabetes with diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Ophthalmology"
DOI: 10.1136/bjo-2022-321297
Abstract: Objectives To explore the possible role of peripheral lesions (PLs) detected by ultrawide field (UWF) imaging system on central neurovascular structure and retinal function. Methods Ninety-seven diabetic patients were included in this cross-sectional study using… read more here.
Keywords: function; without ppl; neurovascular structure; central neurovascular ... See more keywords
Intravitreal gene therapy preserves retinal function in a canine model of CLN2 neuronal ceroid lipofuscinosis.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental eye research"
DOI: 10.2139/ssrn.4208131
Abstract: CLN2 neuronal ceroid lipofuscinosis is a rare hereditary neurodegenerative disorder characterized by deleterious sequence variants in TPP1 that result in reduced or abolished function of the lysosomal enzyme tripeptidyl peptidase 1 (TPP1). Children with this… read more here.
Keywords: function; disease; retinal function; model ... See more keywords
Characterizing the Retinal Function of Psammomys obesus: A Diurnal Rodent Model to Study Human Retinal Function
Sign Up to like & getrecommendations! Published in 2017 at "Current Eye Research"
DOI: 10.3109/02713683.2016.1141963
Abstract: ABSTRACT Purpose: To compare the retinal function of a diurnal murid rodent, Psammomys obesus, with that of Wistar albino rat and human subjects. Materials and methods: Adult Psammomys obesus were captured and transferred to the… read more here.
Keywords: function; human subjects; psammomys obesus; retinal function ... See more keywords
Age-Related Macular or Retinal Degeneration?
Sign Up to like & getrecommendations! Published in 2023 at "Medicina"
DOI: 10.3390/medicina59050920
Abstract: Age-related macular degeneration (AMD) is an eye disease that leads to progressive vision loss. Its prevalence has been increasing due to population aging. Previously, it was commonly believed that the disease affects the central retina,… read more here.
Keywords: related macular; degeneration; age related; age ... See more keywords