Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01948-5
Abstract: Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL) is a bioactive flavonoid found in the root of licorice with reported anti-oxidant and anti-inflammatory activities.… read more here.
Keywords: retinal injury; mir 195; induced retinal; oxidative stress ... See more keywords
The adenosine A2A receptor antagonist protects against retinal mitochondrial injury in association with an altered network of competing endogenous RNAs
Sign Up to like & getrecommendations! Published in 2022 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2022.108981
Abstract: Blockade of adenosine A2A receptors (A2ARs) protects against neuronal damage caused by various brain insults including mitochondrial toxicity, but the precise neuroprotective mechanisms are unclear. Here, we studied the effects of the A2AR antagonist KW6002… read more here.
Keywords: retinal injury; injury; network; antagonist ... See more keywords
Effect of Retinal Injury Induced by Laser Photocoagulation on Visuospatial Memory in Mouse Model
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurosciences in Rural Practice"
DOI: 10.1055/s-0041-1730747
Abstract: Visual pathway reveals the connection between neuronal activity of the brain and eye. The neural networks of brain amplify the retinal signals resulting in the formation of visual image. The laser injury in the retina… read more here.
Keywords: laser; injury induced; induced laser; injury ... See more keywords
Protective effects of hypercapnic acidosis on Ischemia–reperfusion-induced retinal injury
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DOI: 10.1371/journal.pone.0211185
Abstract: Ischemia–reperfusion (I/R) injury is associated with numerous retinal diseases, such as diabetic retinopathy, acute glaucoma, and other vascular retinopathies. Hypercapnic acidosis (HCA) has a protective effect on lung, myocardial, and central nervous system ischemic injury… read more here.
Keywords: hypercapnic acidosis; ischemia reperfusion; injury; retinal injury ... See more keywords
The protective effect of prophylactic ozone administration against retinal ischemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2017 at "Cutaneous and Ocular Toxicology"
DOI: 10.3109/15569527.2016.1156120
Abstract: Abstract Introduction: Retinal ischemia-reperfusion (IR) injury is associated with many ocular diseases. Retinal IR injury leads to the death of retinal ganglion cells (RGCs), loss of retinal function and ultimately vision loss. The aim of… read more here.
Keywords: retinal ischemia; group; reperfusion; injury ... See more keywords
Exploration of the Specific Pathology of HXMM Tablet Against Retinal Injury Based on Drug Attack Model to Network Robustness
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.826535
Abstract: Retinal degenerative diseases are related to retinal injury because of the activation of the complement cascade, oxidative stress-induced cell death mechanisms, dysfunctional mitochondria, chronic neuroinflammation, and production of the vascular endothelial growth factor. Anti-VEGF therapy… read more here.
Keywords: network robustness; pathology; drug; anti vegf ... See more keywords
Natural products: protective effects against ischemia-induced retinal injury
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1149708
Abstract: Ischemic retinal damage, a common condition associated with retinal vascular occlusion, glaucoma, diabetic retinopathy, and other eye diseases, threatens the vision of millions of people worldwide. It triggers excessive inflammation, oxidative stress, apoptosis, and vascular… read more here.
Keywords: ischemia induced; natural compounds; ischemic retinal; induced retinal ... See more keywords
Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.353848
Abstract: Retinal injury after blunt ocular trauma may directly affect prognosis and lead to vision loss. To investigate the pathological changes and molecular mechanisms involved in retinal injury after blunt ocular trauma, we established a weight… read more here.
Keywords: retinal injury; injury; ocular trauma; blunt ocular ... See more keywords