Transplantation of lineage-negative stem cells in pterygopalatine artery ligation induced retinal ischemia–reperfusion injury in mice
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-2941-0
Abstract: Retinal ischemia is a condition associated with retinal degenerative diseases such as glaucoma, diabetic retinopathy, and other optic neuropathies, leading to visual impairment and blindness worldwide. Currently, there is no therapy available for ischemic retinopathies.… read more here.
Keywords: stem cells; retinal ischemia; artery ligation; stem ... See more keywords
TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121484
Abstract: Retinal ischemia-reperfusion injury (IRI) is one of the main pathogenic mechanisms of glaucoma, which are largely unknown, including neuroinflammation and neuronal death in the pathological process. In our previous studies, mesenchymal stem cells (MSCs) have… read more here.
Keywords: mir; reperfusion injury; ischemia reperfusion; retinal ischemia ... See more keywords
Lentiviral vector-mediated expression of C3 transferase attenuates retinal ischemia and reperfusion injury in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119269
Abstract: AIMS Our previous study showed that intravitreal delivery of self-complementary AAV2 (scAAV2)-mediated exoenzyme C3 transferase (C3) can attenuate retinal ischemia/reperfusion (I/R) injury. The current study investigated the neuroprotective effects of lentivirus (LV)-mediated C3 transgene expression… read more here.
Keywords: retinal ischemia; transferase; expression; ischemia reperfusion ... See more keywords
Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2021.101273
Abstract: Objective Retinal ischemic disease is a major cause of vision loss. Current treatment options are limited to late-stage diseases, and the molecular mechanisms of the initial insult are not fully understood. We have previously shown… read more here.
Keywords: retinal ischemia; cell; arginase; ischemia reperfusion ... See more keywords
Management of Acute Retinal Ischemia: Follow the Guidelines!
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2018.03.054
Abstract: Acute retinal arterial ischemia, including vascular transient monocular vision loss (TMVL) and branch (BRAO) and central retinal arterial occlusions (CRAO), are ocular and systemic emergencies requiring immediate diagnosis and treatment. Guidelines recommend the combination of… read more here.
Keywords: retinal ischemia; ischemia follow; acute retinal; management acute ... See more keywords
Neuroprotective Properties of Chlorogenic Acid and 4,5-Caffeoylquinic Acid from Brazilian arnica ( Lychnophora ericoides ) after Acute Retinal Ischemia
Sign Up to like & getrecommendations! Published in 2022 at "Planta Medica"
DOI: 10.1055/a-1903-2387
Abstract: Abstract Lychnophora is a genus of South American flowering plants in the daisy family, popularly known as “Brazilian arnica”. It is used in traditional medicine as an anti-inflammatory and analgesic agent, whose active components are… read more here.
Keywords: brazilian arnica; chlorogenic acid; acute retinal; acid ... See more keywords
Vitreous Haemorrhage and Retinal Neovascularization Secondary to Peripheral Retinal Ischemia as the Presenting Sign of a Disseminated Melanoma.
Sign Up to like & getrecommendations! Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2198003
Abstract: PURPOSE We describe a case of vitreous haemorrhage and retinal neovascularization secondary to peripheral retinal ischemia associated with disseminated melanoma. METHODS A retrospective case report. RESULTS A 48-year-old man presented with vitreous haemorrhage in the… read more here.
Keywords: retinal neovascularization; vitreous haemorrhage; retinal ischemia; peripheral retinal ... See more keywords
[Visualization of retinal blood flow disturbances in acute retinal ischemia syndrome].
Sign Up to like & getrecommendations! Published in 2020 at "Vestnik oftalmologii"
DOI: 10.17116/oftalma2020136051116
Abstract: Vascular disorders account for a significant proportion of acute loss of vision. In recent years, scientific and technical progress in ophthalmology has provided new opportunities in the study of vascular pathology, significantly expanding the understanding… read more here.
Keywords: blood flow; retinal ischemia; ischemia syndrome; acute retinal ... See more keywords
The protective effect of prophylactic ozone administration against retinal ischemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2017 at "Cutaneous and Ocular Toxicology"
DOI: 10.3109/15569527.2016.1156120
Abstract: Abstract Introduction: Retinal ischemia-reperfusion (IR) injury is associated with many ocular diseases. Retinal IR injury leads to the death of retinal ganglion cells (RGCs), loss of retinal function and ultimately vision loss. The aim of… read more here.
Keywords: retinal ischemia; group; reperfusion; injury ... See more keywords
Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.837497
Abstract: Retinal ischemia is a common cause of many retinal diseases, leading to irreversible vision impairment and blindness. Excessive neuroinflammation, including microglial activation and T-cell responses, has been identified as a critical factor associated with neurodegeneration… read more here.
Keywords: baicalein potent; retinal ischemia; potent pro; pro homeostatic ... See more keywords
Pathological Changes and Expression of JAK-STAT Signaling Pathway Hallmark Proteins in Rat Retinas at Different Time Points After Retinal Ischemia Reperfusion Injury
Sign Up to like & getrecommendations! Published in 2022 at "Pathology and Oncology Research"
DOI: 10.3389/pore.2022.1610385
Abstract: Retinal ischemia reperfusion injury (RIRI) is a conventional pathological process in various retinal vascular diseases. Many studies select only one specific time point to apply drugs and then assess the therapeutic effect of drugs; however,… read more here.
Keywords: time; retinal ischemia; time points; ischemia reperfusion ... See more keywords