High-sugar high-fat treatment induces autophagy of retinal microvascular endothelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.02.032
Abstract: OBJECTIVE To investigate the role of high-sugar high-fat treatment in inducing autophagy of rat retinal microvascular endothelial cells. METHODS The optimal concentrations and time points of glucose and oxidized low-density lipoprotein (ox-LDL) in inducing rat… read more here.
Keywords: group; retinal microvascular; microvascular endothelial; treatment ... See more keywords
Lutein and zeaxanthin attenuates VEGF-induced neovascularisation in human retinal microvascular endothelial cells through a Nox4-dependent pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108104
Abstract: Age-related macular degeneration (AMD) and proliferative diabetic retinopathy (DR) are two of the most common and severe causes of vision loss in the population. Both conditions are associated with excessive levels of vascular endothelial growth… read more here.
Keywords: retinal microvascular; induced neovascularisation; vegf induced; lutein zeaxanthin ... See more keywords
Retinal microvascular plasticity in a premature neonate
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174416000817
Abstract: Dilation and abnormal tortuosity of retinal vessels are the hallmarks of severe retinopathy of prematurity (ROP) in premature infants. The stages of ROP are defined by vessel appearance at the interface between the vascular and… read more here.
Keywords: retinal microvascular; plasticity premature; microvascular plasticity; premature ... See more keywords
Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2110264
Abstract: Abstract Purpose Diabetic retinopathy (DR), the major complication of diabetes, is the leading cause of vision loss and blindness globally. Altered circular RNAs (circRNAs) expression has been found to be involved in DR process. Hence,… read more here.
Keywords: retinal microvascular; mir 646; fgf7; circcol1a2 ... See more keywords
Upregulated miR-194-5p suppresses retinal microvascular endothelial cell dysfunction and mitigates the symptoms of hypertensive retinopathy in mice by targeting SOX17 and VEGF signaling
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2119514
Abstract: ABSTRACT Background Hypertensive retinopathy (HR) is a retinal disease that may lead to vision loss and blindness. Sex-determining region Y (SRY)-box (SOX) family transcription factors have been reported to be involved in HR development. In… read more here.
Keywords: hypertensive retinopathy; retinal microvascular; mir 194; mice ... See more keywords
Retinal microvascular diameters: normative data and their use in clinical hypertension.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hypertension"
DOI: 10.1097/hjh.0000000000001421
Abstract: • A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in… read more here.
Keywords: retinal microvascular; microvascular diameters; version; hypertension retinal ... See more keywords
Retinal microvascular abnormalities and risks of incident stroke and its subtypes: The Circulatory Risk in Communities Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003071
Abstract: Background: This study aimed to investigate the association between retinal microvascular abnormalities and the risk of incident stroke and its subtypes in the general Japanese population. Methods: A total of 12 965 residents aged 40–74 years without… read more here.
Keywords: retinal microvascular; microvascular abnormalities; risk; incident stroke ... See more keywords
Retinal Microvascular Changes in Patients with Acute Leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Retina"
DOI: 10.1097/iae.0000000000003504
Abstract: PURPOSE To evaluate the retinal circulation in patients with active acute leukemia, to correlate the perfusion metrics with systemic laboratory values, and to assess the vascular perfusion after leukemia remission. METHODS Longitudinal study of 22… read more here.
Keywords: leukemia; acute leukemia; retinal microvascular; microvascular changes ... See more keywords
tRNA‐derived fragment tRF‐1020 ameliorates diabetes‐induced retinal microvascular complications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17555
Abstract: Transfer RNA (tRNA)‐derived fragments are the non‐coding single‐stranded RNAs involved in several physiological and pathological processes. Herein, we investigated the role of tRF‐1020, a tRNA fragment, in diabetes‐induced retinal microvascular complications. The results showed that… read more here.
Keywords: trf; retinal microvascular; induced retinal; trf 1020 ... See more keywords
Associations of retinal microvascular caliber with intermediate phenotypes of large arterial function and structure: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2019 at "Microcirculation"
DOI: 10.1111/micc.12557
Abstract: Intermediate phenotypes of microcirculation (retinal microvascular caliber) are associated with cardiovascular (CV) risk factors and independently predict CV events. However, the effect of microcirculation variation on the vascular system is unclear. We conducted a systematic… read more here.
Keywords: retinal microvascular; review meta; intermediate phenotypes; systematic review ... See more keywords
Associations of retinal microvascular caliber with large arterial function and structure: A population‐based study of 11 to 12 year‐olds and midlife adults
Sign Up to like & getrecommendations! Published in 2020 at "Microcirculation"
DOI: 10.1111/micc.12642
Abstract: We examined associations between retinal microvascular and large arterial phenotypes to explore relationships between the micro‐ and macro‐vasculature in childhood and midlife. read more here.
Keywords: retinal microvascular; associations retinal; arterial function; caliber large ... See more keywords