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Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202404428
Abstract: Despite of the substantial potential of human‐derived retinal organoids, the degeneration of retinal ganglion cells (RGCs) during maturation limits their utility in assessing the functionality of later‐born retinal cell subtypes. Additionally, conventional analyses primarily rely…
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Keywords:
retinal organoid;
electrophysiological analysis;
development;
organoid development ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8669-9_9
Abstract: The introduction of stem cell-based technologies for the derivation of three-dimensional retinal tissues, the so-called retinal organoids, offers many new possibilities for vision research: Organoids facilitate studies on retinal development and in vitro retinal disease…
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Keywords:
retinal organoid;
embryonic stem;
mouse embryonic;
retinal organoids ... See more keywords
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Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/9717599
Abstract: Objective To study the development process of the human retina, we analyzed the development track of main cell types and transitional cell populations, identifying the retinal organoid cell differentiation-related genes (RDRGs). Methods Single-cell RNA sequencing…
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Keywords:
cell;
development;
retinal organoid;
analysis ... See more keywords