Highly Retina-Permeating and Long-Acting Resveratrol/Metformin Nanotherapeutics for Enhanced Treatment of Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c05824
Abstract: The development of therapeutics for effective treatments of retinal diseases is significantly constrained by various biological barriers. We herein report a nanomedicine strategy to develop nanotherapeutics featured with not only high retinal permeability but also… read more here.
Keywords: resveratrol; macular degeneration; retinal permeability; treatment ... See more keywords
Non‐invasive measurement of retinal permeability in a diabetic rat model
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DOI: 10.1111/micc.12623
Abstract: The gold standard for measuring blood‐retinal barrier permeability is the Evans blue assay. However, this technique has limitations in vivo, including non‐specific tissue binding and toxicity. This study describes a non‐toxic, high‐throughput, and cost‐effective alternative… read more here.
Keywords: invasive measurement; permeability; measurement retinal; non invasive ... See more keywords