Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Progress"
DOI: 10.1002/btpr.2800
Abstract: Blindness as a consequence of degenerative eye diseases (e.g., age‐related macular degeneration and retinitis pigmentosa) is a major health problem and numbers are expected to increase by up to 50% by 2020. Unfortunately, adult mouse… read more here.
Keywords: cells progeny; expansion retinal; retinal stem; stem cells ... See more keywords
Talkin’ about my (re)generation: The who of intrinsic retinal stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.01.022
Abstract: World-wide, two degenerative retinal diseases, glaucoma and age-related macular degeneration, are estimated to affect more than 12% of individuals over the age of 40 (Tham et al., 2014; Wong et al., 2014). Current therapies can… read more here.
Keywords: talkin generation; regeneration; intrinsic retinal; retinal stem ... See more keywords
P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Stem cell research"
DOI: 10.1016/j.scr.2017.05.001
Abstract: Adult retinal stem cells (RSCs) are rare quiescent cells within the ciliary epithelium of the eye, which is made up of non-pigmented N-Cadherin+ve inner and pigmented P-Cadherin+ve outer cell layers. Through FACs and single cell… read more here.
Keywords: vivo; stem cell; retinal stem; cell ... See more keywords
Retinal Stem/Progenitor Cells Derived From Adult Müller Glia for the Treatment of Retinal Degeneration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.749131
Abstract: Over the past two decades, progress in our understanding of glial function has been revolutionary. Within the retina, a subset of glial cells termed the “Müller glia (MG),” have been demonstrated to play key roles… read more here.
Keywords: retinal stem; stem; stem progenitor; ller glia ... See more keywords
Opportunities for agent based modeling of retinal stem cell transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.331868
Abstract: L ate s ta g e b l i n d n e s s a n d v i s u a l impairment (BVI) affects over 400 mi l l ion adu l… read more here.
Keywords: opportunities agent; cell; based modeling; retinal stem ... See more keywords