Development of a protocol for maintaining viability while shipping organoid‐derived retinal tissue
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2997
Abstract: Retinal organoid technology enables generation of an inexhaustible supply of three‐dimensional retinal tissue from human pluripotent stem cells (hPSCs) for regenerative medicine applications. The high similarity of organoid‐derived retinal tissue and transplantable human fetal retina… read more here.
Keywords: medicine; retinal tissue; organoid derived; tissue ... See more keywords
3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2016.11.016
Abstract: No treatments exist to effectively treat many retinal diseases. Retinal pigmented epithelium (RPE) and neural retina can be generated from human embryonic stem cells/induced pluripotent stem cells (hESCs/hiPSCs). The efficacy of current protocols is, however,… read more here.
Keywords: retinal tissue; rgd alginate; tissue; stem cells ... See more keywords
Improvement of retinal tissue perfusion after circuit resistance training in healthy older adults
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.111210
Abstract: PURPOSE To determine the retinal tissue perfusion (RTP) and its relation to cognitive function in healthy older people after an 8-week high-speed circuit resistance training program (HSCT). METHODS Eleven subjects in the HSCT group and… read more here.
Keywords: retinal tissue; tissue perfusion; tissue; healthy older ... See more keywords
Generation of 3D retinal tissue from human pluripotent stem cells using a directed small molecule-based serum-free microwell platform
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-10540-1
Abstract: Retinal degenerative diseases are a leading cause of blindness worldwide with debilitating life-long consequences for the affected individuals. Cell therapy is considered a potential future clinical intervention to restore and preserve sight by replacing lost… read more here.
Keywords: tissue human; pluripotent stem; retinal tissue; platform ... See more keywords
Effects of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms on Retinal Tissue Perfusion in Mild Diabetic Retinopathy Patients Receiving the Medical Food, Ocufolin®.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical ophthalmology"
DOI: 10.2147/opth.s401743
Abstract: Purpose We evaluate the effects of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on retinal tissue perfusion in patients with mild diabetic retinopathy (DR + PM) taking the medical food, Ocufolin®, for 6 months. Methods Prospective, case-controlled study.… read more here.
Keywords: food; tissue perfusion; mthfr polymorphisms; medical food ... See more keywords
Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032727
Abstract: Dravet syndrome (DS) is an epileptic encephalopathy caused by mutations in the Scn1a gene encoding the α1 subunit of the Nav1.1 sodium channel, which is associated with recurrent and generalized seizures, even leading to death.… read more here.
Keywords: tissue shows; dravet syndrome; model; retinal tissue ... See more keywords
Fabrication and Evaluation of Gellan Gum/Hyaluronic Acid Hydrogel for Retinal Tissue Engineering Biomaterial and the Influence of Substrate Stress Relaxation on Retinal Pigment Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175512
Abstract: Cell therapies for age-related macular degeneration (AMD) treatment have been developed by integrating hydrogel-based biomaterials. Until now, cell activity has been observed only in terms of the modulus of the hydrogel. In addition, cell behavior… read more here.
Keywords: stress; hydrogel; retinal tissue; stress relaxation ... See more keywords