High dose cefuroxime causing retinal toxicity in a patient undergoing trabeculectomy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2022.101343
Abstract: Purpose To present a case of severe retinal toxicity secondary to high dose intracameral cefuroxime administered during trabeculectomy glaucoma surgery. We describe the clinical features and management, and describe serial multimodal imaging and electrophysiological findings.… read more here.
Keywords: patient; cefuroxime; toxicity; dose cefuroxime ... See more keywords
Hydroxychloroquine retinopathy: an emerging problem
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DOI: 10.1038/eye.2016.297
Abstract: PurposeThe aim of this case series is to raise awareness of the emerging issue of serious retinal damage caused by the prolonged use of hydroxychloroquine (HCQ) and the importance of adequate and appropriate monitoring of… read more here.
Keywords: hydroxychloroquine; retinopathy emerging; retinal toxicity; emerging problem ... See more keywords
Hydroxychloroquine retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Eye"
DOI: 10.1038/eye.2016.298
Abstract: Hydroxychloroquine (HCQ; Plaquenil) is used increasingly in the management of a variety of autoimmune disorders, with well established roles in dermatology and rheumatology and emerging roles in oncology. Hydroxychloroquine has demonstrated a survival benefit in… read more here.
Keywords: hydroxychloroquine; retinal toxicity; hcq; hcq retinopathy ... See more keywords
OP0133 THE PREVALENCE AND RISK FACTORS OF RETINAL TOXICITY ASSOCIATED WITH LONG-TERM HYDROXYCHLOROQUINE USE
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.328
Abstract: Hydroxychloroquine (HCQ) is commonly used for the treatment of various autoimmune diseases. The medication is generally well-tolerated. However, long-term use after 5 years may increase the risk of retinopathy. One study in 2014 has demonstrated… read more here.
Keywords: hydroxychloroquine; risk; use; retinal toxicity ... See more keywords
RetINal Toxicity And HydroxyChloroquine Therapy (INTACT): protocol for a prospective population-based cohort study
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DOI: 10.1136/bmjopen-2021-053852
Abstract: Purpose Hydroxychloroquine (HCQ) is an important medication for patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other rheumatic diseases. Although it is well-tolerated and cost-effective, the risk of HCQ retinal toxicity is of… read more here.
Keywords: study; prospective population; population based; toxicity ... See more keywords
Value of Microperimetry in Detecting Early Retinal Toxicity of Hydroxychloroquine in Children with Juvenile Systemic Lupus Erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmologica"
DOI: 10.1159/000461595
Abstract: Purpose: To evaluate retinal sensitivity in children who are on hydroxychloroquine (HCQ) for systemic lupus erythematosus using microperimetry and compare the results with those of the Humphrey visual field (HVF) 10-2 and spectral-domain optical coherence… read more here.
Keywords: systemic lupus; microperimetry; lupus erythematosus; retinal toxicity ... See more keywords
Current opinion on hydroxychloroquine-related retinal toxicity screening: where do we stand now?
Sign Up to like & getrecommendations! Published in 2020 at "Lupus"
DOI: 10.1177/0961203320919499
Abstract: Here, we review current hydroxychloroquine screening guidelines and controversies regarding specific screening tests and acceptance of the guidelines. Screening tests are described, and their predictive results are analysed, with special emphasis on early changes. Further… read more here.
Keywords: hydroxychloroquine related; hydroxychloroquine; related retinal; retinal toxicity ... See more keywords
New insights in pathogenic mechanism of hydroxychloroquine retinal toxicity through optical coherence tomography angiography analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Ophthalmology"
DOI: 10.1177/11206721221076313
Abstract: Introduction There is only a unique report with a small sample size studying hydroxychloroquine (HCQ) retinal toxicity with swept-source (SS) optical coherence tomography angiography (OCTA). The aim of this study was to quantify OCTA quantitative… read more here.
Keywords: retinal toxicity; high risk; group; risk group ... See more keywords
Closantel retinal toxicity: Recovery from severe vision loss after corticosteroid therapy.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of ophthalmology"
DOI: 10.1177/11206721221111887
Abstract: PURPOSE To present a relatively rare case of retinal toxicity and consequent severe vision loss due to Closantel ingestion. CASE REPORT A 37-year-old female presented with sudden painless decrease vision in both eyes. She had… read more here.
Keywords: vision loss; closantel; severe vision; retinal toxicity ... See more keywords
Comparison of efficacy and toxicity of intravitreal melphalan formulations for retinoblastoma
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DOI: 10.1371/journal.pone.0235016
Abstract: Objective Intravitreal melphalan injections are commonly used in the treatment for intraocular retinoblastoma. This study compares retinal toxicity and ocular survival between two formulations, with and without propylene glycol (Alkeran vs. Evomela, respectively). Methods A… read more here.
Keywords: toxicity; intravitreal melphalan; ocular survival; retinal toxicity ... See more keywords
Retinal Toxicity Induced by Chemical Agents
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158182
Abstract: Vision is an important sense for humans, and visual impairment/blindness has a huge impact in daily life. The retina is a nervous tissue that is essential for visual processing since it possesses light sensors (photoreceptors)… read more here.
Keywords: chemical agents; retinal toxicity; toxicity induced; induced chemical ... See more keywords