Structural Development of Silicon‐Containing Retinoids: Structure–Activity Relationship Study of the Hydrophobic Pharmacophore of Retinobenzoic Acids Using Silyl Functionalities
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DOI: 10.1002/cmdc.202200176
Abstract: We designed and synthesized a series of retinobenzoic acids bearing various silyl functionalities in order to explore in detail the structure‐activity relationship (SAR) at the hydrophobic moiety of retinoids. Among the synthesized compounds, 24 c bearing… read more here.
Keywords: retinobenzoic acids; structure activity; silyl functionalities; activity relationship ... See more keywords