PRC1 gene silencing inhibits proliferation, invasion, and angiogenesis of retinoblastoma cells through the inhibition of the Wnt/β‐catenin signaling pathway
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DOI: 10.1002/jcb.28942
Abstract: Retinoblastoma is an ocular malignancy occurring in childhood. The current study evaluates the ability of silenced PRC1 on retinoblastoma cell proliferation, and angiogenesis via the Wnt/β‐catenin signaling pathway. A total of 36 cases of retinoblastoma… read more here.
Keywords: retinoblastoma cells; angiogenesis; catenin; proliferation ... See more keywords
Sp1-mediated up-regulation of lnc00152 promotes invasion and metastasis of retinoblastoma cells via the miR-30d/SOX9/ZEB2 pathway
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DOI: 10.1007/s13402-020-00522-8
Abstract: Purpose Previously, we found that long non-coding RNA (lncRNA) MEG3 may act as a tumour suppressor in retinoblastoma. Overall, however, little is known about the role of lncRNAs in retinoblastoma. Here, we aimed to determine… read more here.
Keywords: retinoblastoma cells; lnc00152; retinoblastoma; sox9 zeb2 ... See more keywords
Knockdown of NRMT enhances sensitivity of retinoblastoma cells to cisplatin through upregulation of the CENPA/Myc/Bcl2 axis
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DOI: 10.1038/s41420-021-00622-w
Abstract: Chemotherapy resistance of tumor cells causes failure in anti-tumor therapies. Recently, N-terminal regulator of chromatin condensation 1 methyltransferase (NRMT) is abnormally expressed in different cancers. Hence, we speculate that NRMT may pay a crucial role… read more here.
Keywords: cenpa; retinoblastoma; retinoblastoma cells; myc ... See more keywords