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Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co‐Administration of a Retinoid Antagonist in Mice

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Published in 2021 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4291

Abstract: The growth plates are key engines of skeletal development and growth and contain a top reserve zone followed by maturation zones of proliferating, prehypertrophic, and hypertrophic/mineralizing chondrocytes. Trauma or drug treatment of certain disorders can… read more here.

Keywords: closure; growth plate; drug; growth ... See more keywords