Selective production of retinol by engineered Saccharomyces cerevisiae through the expression of retinol dehydrogenase
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28004
Abstract: Retinol is a fat‐soluble vitamin A that is widely used in the food and pharmaceutical industries. Currently, retinol is commercially produced by chemical synthesis. Microbial production of retinol has been alternatively explored but restricted to… read more here.
Keywords: saccharomyces cerevisiae; production retinol; retinol; production ... See more keywords
Improving long-term stability of retinol in dried blood spots and quantification of its levels via a novel LC-MS/MS method
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02183-5
Abstract: Vitamin A deficiency (VAD) is a major micronutrient deficiency in children. Although plasma and serum retinol levels are proposed as the key indicators of VAD, collecting and transporting plasma and serum are difficult and inconvenient… read more here.
Keywords: plasma; method; dbs retinol; dried blood ... See more keywords
sLRP1'in up retinol keeps the gut SAAfe.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.10.013
Abstract: Retinol is shuttled to myeloid cells for conversion to retinoic acid, but the receptor facilitating uptake of SAA:retinol complexes on myeloid cells is unknown. In a recent issue of Science, Bang et al. (2021) use genetic… read more here.
Keywords: keeps gut; gut saafe; slrp1 retinol; retinol keeps ... See more keywords
Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00517
Abstract: β-Amyloid (Aβ) aggregation is causally linked to Alzheimer's disease. On the basis of in vitro and transgenic animal studies, transthyretin (TTR) is hypothesized to provide neuroprotection against Aβ toxicity by binding to Aβ and inhibiting… read more here.
Keywords: protein; aggregation; hrbp; ttr ... See more keywords
Metabolomic Profiling of Serum Retinol in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09698-w
Abstract: The role of retinol in the prevention of multifactorial chronic diseases remains uncertain, and there is sparse evidence regarding biological actions and pathways implicated in its effects on various outcomes. The aim is to investigate… read more here.
Keywords: serum retinol; alpha tocopherol; retinol; tocopherol beta ... See more keywords
Effectiveness of a Food-Based Intervention to Increase Breast Milk Vitamin A Content at One Month of Infancy
Sign Up to like & getrecommendations! Published in 2020 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzaa041_034
Abstract: Vitamin A requirements in early infancy are met only by breast milk intake. It is critical to ensure adequate breast milk vitamin A levels which also helps develop liver stores. The objective of the study… read more here.
Keywords: intervention; breast milk; milk vitamin; retinol ... See more keywords
Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abf9232
Abstract: Description SAAving vitamin A–mediated immunity The vitamin A metabolite retinol is critical for B and T cell development and homing to the gut. Intestinal myeloid cells such as dendritic cells and macrophages take up retinol… read more here.
Keywords: immunity; myeloid cells; intestinal myeloid; retinol ... See more keywords
Stability of serum retinol-binding protein at −20⁰C
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical Biochemistry"
DOI: 10.1177/00045632221090896
Abstract: Introduction Retinol is a common indicator of vitamin A status. Retinol forms a complex with retinol binding protein (RBP) at a ratio of 1:1 and is thus transported in the serum. RBP is easily measured… read more here.
Keywords: binding protein; retinol; retinol binding; serum ... See more keywords
Retinol and α-Tocopherol Levels in the Serum and Subcutaneous Adipose Tissue of Newly Diagnosed Basal Cell Carcinoma Patients
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v48i10.3491
Abstract: Background: Nonmelanoma skin cancers are the most frequently occurring skin cancers. Vitamin A is involved in epithelial cell differentiation and may control skin tumor development. Vitamin E is a powerful lipophilic antioxidant that can quench… read more here.
Keywords: control; bcc patients; tocopherol; retinol ... See more keywords
Integrative Analysis of Human Plasma Proteome/Metabolome Reveals Central Role for Phospholipid, Retinol, and Histidine Metabolism after Gastric Bypass
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.2337/db18-263-lb
Abstract: Bariatric surgery has emerged as a potent approach to improve obesity-related metabolic comorbidities including type 2 diabetes (T2D). However, molecular mechanisms responsible for metabolic improvement after bariatric surgery remain incompletely understood. We profiled and integrated… read more here.
Keywords: plasma proteome; research; analysis; self ... See more keywords
Serum retinol, β-carotene, and α-tocopherol as biomarkers for disease risk and milk production in periparturient dairy cows.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dairy science"
DOI: 10.3168/jds.2020-18693
Abstract: The effectiveness of using serum vitamin concentrations as biomarkers to predict diseases in dairy cows during the periparturient period is not well known. The objective of this study was to evaluate the association between serum… read more here.
Keywords: milk; carotene; serum; retinol ... See more keywords