Selective production of retinol by engineered Saccharomyces cerevisiae through the expression of retinol dehydrogenase
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28004
Abstract: Retinol is a fat‐soluble vitamin A that is widely used in the food and pharmaceutical industries. Currently, retinol is commercially produced by chemical synthesis. Microbial production of retinol has been alternatively explored but restricted to… read more here.
Keywords: saccharomyces cerevisiae; production retinol; retinol; production ... See more keywords
Retinol dehydrogenase 12 (RDH12): Role in vision, retinal disease and future perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107793
Abstract: Retinol dehydrogenase 12 (RDH12) is an NADPH-dependent retinal reductase, which is expressed in the inner segments of the photoreceptors. It functions as part of the visual cycle, which is a series of enzymatic reactions required… read more here.
Keywords: retinol dehydrogenase; dehydrogenase rdh12; disease; role vision ... See more keywords
Retinol dehydrogenase 13 deficiency diminishes carbon tetrachloride-induced liver fibrosis in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2016.11.010
Abstract: Retinol dehydrogenase 13 (RDH13) is a mitochondrion-localized member of the short-chain dehydrogenases/reductases (SDRs) superfamily that participates in metabolism of some compounds. Rdh13 mRNA is most highly expressed in mouse liver. Rdh13 deficiency reduces the extent… read more here.
Keywords: retinol dehydrogenase; fibrosis; dehydrogenase deficiency; deficiency diminishes ... See more keywords
A new phenotype of syndromic retinitis pigmentosa with myopathy is caused by mutations in retinol dehydrogenase 11
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Genetics"
DOI: 10.1111/cge.14108
Abstract: Retinol dehydrogenase 11 (RDH11) is an 11‐cis‐retinol dehydrogenase that has a well‐characterized, albeit auxiliary role in the retinoid cycle. Diseases caused by mutations in the RDH11 gene are very rare, and only one affected family… read more here.
Keywords: phenotype syndromic; retinol dehydrogenase; retinitis pigmentosa; caused mutations ... See more keywords