AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis
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DOI: 10.1371/journal.pone.0276298
Abstract: Objective To evaluate efficacy of a novel adeno-associated virus (AAV) vector, AAV2/4-RS1, for retinal rescue in the retinoschisin knockout (Rs1-KO) mouse model of X-linked retinoschisis (XLRS). Brinzolamide (Azopt®), a carbonic anhydrase inhibitor, was tested for… read more here.
Keywords: aav2 rs1; rs1; retinoschisin knockout; mice ... See more keywords