The Retro‐Claisen Rearrangement of 2‐Vinylcyclopropylcarbonyl Substrates and the Question of its Synthetic Potential
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DOI: 10.1002/ejoc.202000136
Abstract: The retro-Claisen [3,3]-sigmatropic rearrangement of ,-enoyl compounds allows to form a CO bond while breaking a CC bond in a concerted process. It is rarely observed with acyclic substrates. However, when the alkene and carbonyl… read more here.
Keywords: rearrangement; retro claisen; claisen rearrangement; rearrangement vinylcyclopropylcarbonyl ... See more keywords
Asymmetric Retro-Claisen Reaction Catalyzed by Chiral Aza-Bisoxazoline-Zn(II) Complex: Enantioselective Synthesis of α-Arylated Ketones.
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DOI: 10.1021/acs.orglett.3c00372
Abstract: An asymmetric retro-Claisen reaction of α-monosubstituted β-diketones and quinones (or quinone imine) has been developed under the catalysis of a chiral aza-bisoxazoline-Zn(II) complex. The reaction proceeds via a sequence of conjugate addition, arylation, hemiketal anion-initiated… read more here.
Keywords: aza bisoxazoline; asymmetric retro; reaction; claisen reaction ... See more keywords