Modulating Copper(II) Coordination and Antimicrobial Activity: Effects of d-Amino Acid Substitution and Retro-Inverso Modification in Human Saliva MUC7 Peptide
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic Chemistry"
DOI: 10.1021/acs.inorgchem.5c00438
Abstract: Fragments of MUC7, a salivary protein involved in nonimmune defense, arise from proteolytic cleavage in saliva and exhibit antimicrobial properties. However, their therapeutic use is limited by low stability due to further degradation. To address… read more here.
Keywords: antimicrobial activity; chemistry; retro inverso; muc7 ... See more keywords
FRI0512 RETRO-INVERSO TAT-BECLIN-1 INDUCES SYNOVIAL FIBROSIS AND DOES NOT PROTECT CARTILAGE FROM DEGENERATION IN A MOUSE MODEL OF OA
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2680
Abstract: Background Beclin-1 is a component of the autophagy pathway necessary for formation of autophagosomes, contributing to autophagy-mediated cellular homeostasis. Enhancing autophagy through inhibition of mTOR activity, either via genetic deletion in chondrocytes or intra-articular injection… read more here.
Keywords: inverso tat; beclin; retro inverso; tat beclin ... See more keywords