FRI0512 RETRO-INVERSO TAT-BECLIN-1 INDUCES SYNOVIAL FIBROSIS AND DOES NOT PROTECT CARTILAGE FROM DEGENERATION IN A MOUSE MODEL OF OA
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DOI: 10.1136/annrheumdis-2019-eular.2680
Abstract: Background Beclin-1 is a component of the autophagy pathway necessary for formation of autophagosomes, contributing to autophagy-mediated cellular homeostasis. Enhancing autophagy through inhibition of mTOR activity, either via genetic deletion in chondrocytes or intra-articular injection… read more here.
Keywords: inverso tat; beclin; retro inverso; tat beclin ... See more keywords