Pathway Retrofitting Yields Insights into the Biosynthesis of Anthraquinone-Fused Enediynes.
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DOI: 10.1021/jacs.1c03911
Abstract: Anthraquinone-fused enediynes (AQEs) are renowned for their distinctive molecular architecture, reactive enediyne warhead, and potent anticancer activity. Although the first members of AQEs, i.e., dynemicins, were discovered three decades ago, how their nitrogen-containing carbon skeleton… read more here.
Keywords: insights biosynthesis; anthraquinone fused; pathway retrofitting; fused enediynes ... See more keywords