Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50
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DOI: 10.1242/jcs.196758
Abstract: ABSTRACT Retromer and the associated actin-polymerizing WASH complex are essential for the endocytic recycling of a wide range of integral membrane proteins. A hereditary Parkinson's-disease-causing point mutation (D620N) in the retromer subunit VPS35 perturbs retromer's… read more here.
Keywords: retromer wash; interaction network; retromer; wash complex ... See more keywords