The mutational load in natural populations is significantly affected by high primary rates of retroposition
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2013043118
Abstract: Significance The phenomenon of retroposition (the reintegration of reverse-transcribed RNA into the genome) has been well studied in comparisons between species and has been identified as a source of evolutionary innovation. However, less attention has… read more here.
Keywords: mutational load; natural populations; retroposition mutational; negative effects ... See more keywords
mRNA Vaccines: Why Is the Biology of Retroposition Ignored?
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13050719
Abstract: The major advantage of mRNA vaccines over more conventional approaches is their potential for rapid development and large-scale deployment in pandemic situations. In the current COVID-19 crisis, two mRNA COVID-19 vaccines have been conditionally approved… read more here.
Keywords: mrna vaccines; mrna based; vaccine; biology ... See more keywords