Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers.
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DOI: 10.1101/gr.231837.117
Abstract: Long interspersed nuclear element-1 (LINE-1 or L1) retrotransposons are normally suppressed in somatic tissues mainly due to DNA methylation and antiviral defense. However, the mechanism to suppress L1s may be disrupted in cancers, thus allowing… read more here.
Keywords: retrotransposition gastrointestinal; retrotransposition; expression; immune signatures ... See more keywords