The HP1 box of KAP1 organizes HP1α for silencing of endogenous retroviral elements in embryonic stem cells
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DOI: 10.1038/s41467-025-60279-2
Abstract: Repression of endogenous retroviral elements (ERVs) is facilitated by KAP1 (KRAB-associated protein 1)-containing complexes, however the underlying mechanism remains unclear. Here, we show that binding of KAP1 to the major component of the heterochromatin spreading… read more here.
Keywords: retroviral elements; kap1; endogenous retroviral; stem cells ... See more keywords