Articles with "retroviral vectors" as a keyword



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Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells

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Published in 2017 at "Gene Therapy"

DOI: 10.1038/gt.2017.20

Abstract: Correction of patient-specific induced pluripotent stem cells (iPSC) upon gene delivery through retroviral vectors offers new treatment perspectives for monogenetic diseases. Gene-modified iPSC clones can be screened for safe integration sites and differentiated into transplantable… read more here.

Keywords: transgene expression; retroviral vectors; expression; pluripotent stem ... See more keywords