Synergistic anti‐depressive effect of combination treatment of Brexpiprazole and selective serotonin reuptake inhibitors on forced swimming test in mice
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12316
Abstract: Selective serotonin reuptake inhibitors (SSRIs) are used to treat major depressive disorder (MDD) and other psychiatric disorders (e.g., obsessive compulsive disorder, social anxiety disorder, and panic disorder). In MDD treatment, SSRIs do not show remission… read more here.
Keywords: effect; reuptake inhibitors; selective serotonin; serotonin reuptake ... See more keywords
Comparative transcriptomics implicate mitochondrial and neurodevelopmental impairments in larval zebrafish (Danio rerio) exposed to two selective serotonin reuptake inhibitors (SSRIs).
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.110934
Abstract: Pharmaceuticals and personal care products are emerging contaminants that are increasingly detected in the environment worldwide. Certain classes of pharmaceuticals, such as selective serotonin reuptake inhibitors (SSRIs), are a major environmental concern due to their… read more here.
Keywords: selective serotonin; serotonin reuptake; inhibitors ssris; exposure ... See more keywords
Modeling the acute pharmacological response to selective serotonin reuptake inhibitors in human brain using simultaneous PET/MR imaging
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2019.04.001
Abstract: Pharmacological imaging of the effects of selective serotonin reuptake inhibitors (SSRI) may aid the clarification of their mechanism of action and influence treatment of highly prevalent neuropsychiatric conditions if the detected effects could be related… read more here.
Keywords: selective serotonin; serotonin reuptake; response; pharmacological response ... See more keywords
Selective serotonin reuptake inhibitors (SSRI) affect murine bone lineage cells.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117827
Abstract: AIMS Data suggest pharmacological treatment of depression with selective serotonin reuptake inhibitors (SSRI) may impair bone health. Our group has previously modeled compromised craniofacial healing after treatment with sertraline, a commonly prescribed SSRI, and hypothesized… read more here.
Keywords: selective serotonin; serotonin reuptake; lineage; treatment ... See more keywords
Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.08.012
Abstract: The use of antidepressants in pregnant women is rising, with rates up to 7.5% in the United States. Selective serotonin reuptake inhibitors (SSRIs) are currently the most common antidepressant prescribed to pregnant women. The teratogenic… read more here.
Keywords: selective serotonin; serotonin reuptake; reuptake inhibitors; stem cell ... See more keywords
Multiple possible inaccuracies cast doubt on a recent report suggesting selective serotonin reuptake inhibitors to be toxic and ineffective
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropsychiatrica"
DOI: 10.1017/neu.2017.23
Abstract: According to a systematic review on the use of selective serotonin reuptake inhibitors (SSRIs) in adult depression that was recently published in BMC Psychiatry, the results of which have been widely disseminated in lay media,… read more here.
Keywords: selective serotonin; serotonin reuptake; possible inaccuracies; analysis ... See more keywords
What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00490
Abstract: Dual inhibition of serotonin and norepinephrine transporters (hSERT and hNET) gives greatly improved efficacy and tolerability for treating major depressive disorder (MDD) compared with selective reuptake inhibitors. Pioneer studies provided valuable information on structure, function,… read more here.
Keywords: serotonin norepinephrine; norepinephrine transporters; reuptake inhibitors; mechanism ... See more keywords
Comparative effectiveness of cognitive behavioral treatment, serotonin, and serotonin noradrenaline reuptake inhibitors for anxiety in children and adolescents: a network meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Nordic Journal of Psychiatry"
DOI: 10.1080/08039488.2022.2069858
Abstract: Abstract Aim Cognitive behavioral treatment (CBT) and selective serotonin reuptake inhibitors (SSRIs) are considered first-line treatments for childhood anxiety disorders (ADs). The objective of this current analysis was to conduct a network meta-analysis to evaluate… read more here.
Keywords: serotonin; cognitive behavioral; reuptake inhibitors; analysis ... See more keywords
Efficacy and safety of serotonin reuptake inhibitors (SSRI) and serotonin noradrenaline reuptake inhibitors (SNRI) for children and adolescents with anxiety disorders: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Nordic Journal of Psychiatry"
DOI: 10.1080/08039488.2022.2075460
Abstract: Abstract Purpose To assess the efficacy and safety of selective serotonin reuptake inhibitors (SSRIs) and selective noradrenaline reuptake inhibitors (SNRIs) in comparison with various control contingencies (e.g. pill placebo and cognitive behavioral treatment) for pediatric… read more here.
Keywords: anxiety disorders; reuptake inhibitors; reuptake; efficacy safety ... See more keywords
Selective serotonin reuptake inhibitors for the treatment of chronic pruritus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2018.1456639
Abstract: Chronic pruritus is defined as itch lasting 6 weeks or longer. Although chronic pruritus has a significant burden of disease, there are currently no FDA approved treatments specifically targeting p... read more here.
Keywords: selective serotonin; serotonin reuptake; treatment; pruritus ... See more keywords
Selective serotonin reuptake inhibitors in major depression disorder treatment: an umbrella review on systematic reviews
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Psychiatry in Clinical Practice"
DOI: 10.1080/13651501.2020.1782433
Abstract: Abstract Background Major depressive disorder (MDD) is a common mental problem and one of the leading causes of disability worldwide. SSRIs are the most commonly prescribed types of antidepressants which are called Selective Serotonin Reuptake… read more here.
Keywords: selective serotonin; serotonin reuptake; reuptake inhibitors; systematic reviews ... See more keywords