Investigation of the Potency of KALA and REV Cell‐Penetrating Peptides for In Vitro/In Vivo Delivery of an HPV Multiepitope DNA Construct
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Peptide Science"
DOI: 10.1002/psc.70000
Abstract: Developing human papillomavirus (HPV) therapeutic DNA vaccines requires an effective delivery system, such as cell‐penetrating peptides (CPPs). In the current study, the multiepitope DNA constructs harboring the immunogenic and conserved epitopes of the L1, L2,… read more here.
Keywords: kala rev; delivery; rev; penetrating peptides ... See more keywords
Premature Stop Codon at Residue 101 within HIV-1 Rev Does Not Influence Viral Replication of Clade BC but Severely Reduces Viral Fitness of Clade B
Sign Up to like & getrecommendations! Published in 2019 at "Virologica Sinica"
DOI: 10.1007/s12250-019-00179-0
Abstract: HIV-1 Rev is an accessory protein that plays a key role in nuclear exportation, stabilization, and translation of the viral mRNAs. Rev of HIV-1 clade BC often shows a truncation of 16 AAs due to… read more here.
Keywords: premature stop; rev; clade; stop codon ... See more keywords
Rev‐erb regulation of cholesterologenesis
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.02.006
Abstract: ABSTRACT REV‐ERB&agr; and REV‐ERB&bgr; are heme regulated nuclear receptors that are known to regulate metabolic pathways. We previously demonstrated that treatment of mice with synthetic REV‐ERB agonists suppressed plasma cholesterol levels and the hepatic levels… read more here.
Keywords: rev erb; expression; rev; cholesterol levels ... See more keywords
Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114807
Abstract: The molecular events underlying aristolochic acid (AA) nephropathy are poorly understood, and specific therapies for treatment of AA nephropathy are still lacking. Here we aimed to investigate a potential role of REV-ERBα and ferroptosis in… read more here.
Keywords: rev erb; ferroptosis; renal injury; rev ... See more keywords
O31 Evaluating Success of Paraprofessional Educators in a Pilot Adolescent Classroom Intervention: Rev It Up!
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nutrition Education and Behavior"
DOI: 10.1016/j.jneb.2020.04.043
Abstract: Objective To evaluate Rev It Up!, a pilot nutrition education curriculum for teens, when it is taught by either paraprofessional or professional educators. Use of Theory or Research Research shows teens consume low levels of… read more here.
Keywords: intervention; nutrition education; rev; curriculum ... See more keywords
Development of Brucella melitensis Rev.1 ΔOmp19 mutants with DIVA feature and comparison of their efficacy against three commercial vaccines in a mouse model.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.02.006
Abstract: Brucella is an intracellular zoonotic pathogen that can affect many hosts. Brucella melitensis Rev.1 is a live attenuated, is one of the most effective vaccine strain against brucellosis. It can be used safely in sheep,… read more here.
Keywords: brucella; rev; melitensis rev; commercial vaccines ... See more keywords
Development of a Novel Dual-Order Protein-Based Nanodelivery Carrier That Rapidly Targets Low-Grade Gliomas with Microscopic Metastasis in Vivo
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c03073
Abstract: Clinically diagnosing low-grade gliomas and microscopic metastatic tumors in the spinal cord using magnetic resonance imaging (MRI) is challenging, as the blood–brain barrier (BBB) almost completely excludes the MRI contrast agent gadopentetate dimeglumine, GdDTPA (Magnevist),… read more here.
Keywords: gliomas microscopic; rev; rev ang;
Role of the circadian nuclear receptor REV-ERBα in dorsal raphe serotonin synthesis in mood regulation
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06647-y
Abstract: Affective disorders are frequently associated with disrupted circadian rhythms. The existence of rhythmic secretion of central serotonin (5-hydroxytryptamine, 5-HT) pattern has been reported; however, the functional mechanism underlying the circadian control of 5-HTergic mood regulation… read more here.
Keywords: circadian nuclear; rev erb; mood regulation; rev ... See more keywords
Experimental and numerical analysis on the cutting force, cutting temperature, and tool wear of alloy steel (4340) during turning process
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DOI: 10.1063/5.0227710
Abstract: This paper focuses primarily on the wear behavior observed in AISI4340 steel when machining with a multi-layered coated carbide tool. Numerical and experimental examination is processed out to predict the wear performance of AISI 4340… read more here.
Keywords: temperature; tool; steel; rev ... See more keywords
Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles
Sign Up to like & getrecommendations! Published in 2018 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2017.0306
Abstract: Abstract Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those untargeted by antiretroviral drugs.… read more here.
Keywords: production; rev; hiv; nucleolar localization ... See more keywords
Circadian nuclear receptor Rev-erbα is expressed by platelets and potentiates platelet activation and thrombus formation
Sign Up to like & getrecommendations! Published in 2022 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehac109
Abstract: Abstract Aims Adverse cardiovascular events have day/night patterns with peaks in the morning, potentially related to endogenous circadian clock control of platelet activation. Circadian nuclear receptor Rev-erbα is an essential and negative component of the… read more here.
Keywords: rev; platelet activation; rev erb;