REV1-POL ζ Inhibition and Cancer Therapy.
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DOI: 10.1016/j.molcel.2019.07.012
Abstract: In a recent issue of Cell, Wojtaszek et al. (2019) reported a small-molecule inhibitor of mutagenic translesion DNA synthesis, which targets the interaction between REV1 and REV7, sensitizes cancer cells to cisplatin in vitro and in vivo, and… read more here.
Keywords: rev1 pol; pol inhibition; inhibition cancer; cancer ... See more keywords