Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26543
Abstract: Monoclonal antibodies (mAbs) currently dominate the biopharmaceutical sector due to their potency and efficacy against a range of disease targets. These proteinaceous therapeutics are, however, susceptible to unfolding, mis‐folding, and aggregation by environmental perturbations. Aggregation… read more here.
Keywords: aggregation; flow reveal; extensional flow; reveal diverse ... See more keywords
Metagenomic data reveal diverse fungal and algal communities associated with the lichen symbiosis
Sign Up to like & getrecommendations! Published in 2020 at "Symbiosis"
DOI: 10.1007/s13199-020-00699-4
Abstract: Lichens have traditionally been considered the symbiotic phenotype from the interactions of a single fungal partner and one or few photosynthetic partners. However, lichen symbioses have been shown to be far more complex and may… read more here.
Keywords: fungal algal; data reveal; reveal diverse; diverse fungal ... See more keywords
Gene-enhancer variants reveal diverse TCR-mediated differentiation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3729
Abstract: The transcription factor IRF4 acts as a 'rheostat' for TCR signaling. Discrete levels of IRF4 can activate distinct transcriptional programs in T cells due to binding sites of variable affinity in groups of target genes. read more here.
Keywords: gene enhancer; tcr mediated; diverse tcr; enhancer variants ... See more keywords
Metatranscriptomes reveal the diverse responses of Thaumarchaeota ecotypes to environmental variations in the northern slope of the South China Sea.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental microbiology"
DOI: 10.1111/1462-2920.16289
Abstract: Thaumarchaeota are among the most abundant prokaryotes in the ocean, playing important roles in carbon and nitrogen cycling. Marine Thaumarchaeota ecotypes exhibit depth-related diversification and seasonal changes. However, transcriptomic activities concerning niche partitioning among thaumarchaeal… read more here.
Keywords: metatranscriptomes reveal; reveal diverse; water; marine thaumarchaeota ... See more keywords