Molecular Dynamics Simulations Reveal Structural Interconnections within Sec14-PH Bipartite Domain from Human Neurofibromin
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DOI: 10.3390/ijms23105707
Abstract: Neurofibromin, the main RasGAP in the nervous system, is a 2818 aa protein with several poorly characterized functional domains. Mutations in the NF1-encoding gene lead to an autosomal dominant syndrome, neurofibromatosis, with an incidence of… read more here.
Keywords: dynamics simulations; reveal structural; molecular dynamics; simulations reveal ... See more keywords