Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing.
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DOI: 10.1016/j.celrep.2017.11.031
Abstract: A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for identification of variants present at the single-mitochondrion level in individual mouse and human neuronal cells,… read more here.
Keywords: single mitochondrion; single nucleotide; revealed single; nucleotide variant ... See more keywords