Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109797
Abstract: Membrane lipids and their metabolism have key functions in neurotransmission. Here we provide a quantitative lipid inventory of mouse and rat synaptic junctions. To this end, we developed a multiomics extraction and analysis workflow to… read more here.
Keywords: metabolism; multiomics synaptic; synaptic junctions; reveals altered ... See more keywords
Plasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia"
DOI: 10.1111/epi.18256
Abstract: Idiopathic epilepsy (IE) is the most common chronic neurological disease in dogs and an established natural animal model for human epilepsy types with genetic and unknown etiology. However, the metabolic pathways underlying IE remain largely… read more here.
Keywords: metabolome reveals; altered oxidative; epilepsy; idiopathic epilepsy ... See more keywords