Quantitative investigation reveals distinct phases in Drosophila sleep
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-01883-y
Abstract: The fruit fly, Drosophila melanogaster , has been used as a model organism for the molecular and genetic dissection of sleeping behaviors. However, most previous studies were based on qualitative or semi-quantitative characterizations. Here we… read more here.
Keywords: reveals distinct; investigation reveals; quantitative investigation; fly ... See more keywords
Multiomic spatial analysis reveals a distinct mucosa-associated virome
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DOI: 10.1080/19490976.2023.2177488
Abstract: ABSTRACT The human gut virome has been increasingly explored in recent years. However, nearly all virome-sequencing efforts rely solely on fecal samples and few studies leverage multiomic approaches to investigate phage–host relationships. Here, we combine… read more here.
Keywords: spatial analysis; reveals distinct; distinct mucosa; multiomic spatial ... See more keywords
Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals
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DOI: 10.1093/gigascience/gix036
Abstract: Abstract The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be… read more here.
Keywords: reveals distinct; profiling reveals; distinct differences; plasma lipid ... See more keywords
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
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DOI: 10.15252/embr.201846171
Abstract: Microglia are specialized parenchymal‐resident phagocytes of the central nervous system (CNS) that actively support, defend and modulate the neural environment. Dysfunctional microglial responses are thought to worsen CNS diseases; nevertheless, their impact during neuroinflammatory processes… read more here.
Keywords: single cell; reveals distinct; distinct inflammation; cell transcriptomics ... See more keywords
Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies
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DOI: 10.15252/emmm.202216789
Abstract: Many efforts targeting amyloid‐β (Aβ) plaques for the treatment of Alzheimer's Disease thus far have resulted in failures during clinical trials. Regional and temporal heterogeneity of efficacy and dependence on plaque maturity may have contributed… read more here.
Keywords: whole brain; reveals distinct; microscopy; efficacy ... See more keywords