In situ fluorescence imaging reveals that mitochondrial H2O2 mediates lysosomal dysfunction in depression.
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DOI: 10.1039/d2cc00431c
Abstract: We constructed two fluorescent probes for monitoring H2O2 in the mitochondria and lysosomes. Fluorescence imaging reveals that mitochondrial H2O2 mediates reduced GCase activity in lysosomes in the brains of mice with depression. This work provides… read more here.
Keywords: reveals mitochondrial; depression; fluorescence imaging; mitochondrial h2o2 ... See more keywords