Discovery of brevijanazines from Aspergillus brevijanus reveals the molecular basis for p-nitrobenzoic acid in fungi.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01679f
Abstract: The brevijanazines are novel p-nitrobenzoylated piperazines isolated from Aspergillus brevijanus. Their structures were elucidated by spectroscopic analysis, X-ray crystallography and total synthesis. Heterologous biosynthesis, precursor feeding and in vitro microsomal assays unveiled the biosynthetic pathway… read more here.
Keywords: aspergillus brevijanus; nitrobenzoic acid; discovery brevijanazines; reveals molecular ... See more keywords
Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2507559122
Abstract: Nuclear pore complexes (NPCs) enable rapid, selective, and robust nucleocytoplasmic transport. To explain how transport emerges from the system components and their interactions, we used experimental data and theoretical information to construct an integrative Brownian… read more here.
Keywords: transport; nucleocytoplasmic transport; integrative mapping; mapping reveals ... See more keywords
Metabolomics analysis reveals molecular linkages for the impact of vitamin D on childhood allergic airway diseases
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13785
Abstract: Several studies have reported the relevance between serum vitamin D and allergic immunoglobulin E (IgE) responses and atopic diseases. However, a metabolomics‐based approach to the impacts of vitamin D on allergic reactions remains unclear. read more here.
Keywords: linkages impact; molecular linkages; reveals molecular; impact vitamin ... See more keywords
Proteomics Reveals Molecular Changes in Insomnia Patients with More Dreams
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/6181943
Abstract: Background Insomnia is a sleep disorder and the cause of many healthy problems. However, there are few studies on patients with insomnia and dreaminess at present. Therefore, this study is aimed at exploring the pathological… read more here.
Keywords: insomnia patients; ppi network; patients dreams; reveals molecular ... See more keywords
Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/0008-5472.can-23-1878
Abstract: Characterization of the proteogenomic landscape of colorectal cancer during progression provides a multiomic map detailing the alterations in each stage of carcinogenesis and suggesting potential diagnostic and therapeutic approaches for patients. read more here.
Keywords: colorectal cancer; cancer; proteogenomic profiling; reveals molecular ... See more keywords
Machine Learning Reveals Molecular Similarity and Fingerprints in Structural Aberrations of Somatic Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Symmetry"
DOI: 10.3390/sym15051023
Abstract: Structural aberrations (SA) have been shown to play an essential role in the occurrence and development of cancer. SAs are typically characterized by copy number alteration (CNA) dose and distortion length. Although sequencing techniques and… read more here.
Keywords: learning reveals; machine learning; reveals molecular; molecular similarity ... See more keywords