Dissecting Heterogeneity Reveals a Unique BAMBIhighMFGE8high Subpopulation of Human UC‐MSCs
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202510
Abstract: Mixed human umbilical cord‐derived mesenchymal stem cells (UC‐MSCs) are widely applied in clinical trials to treat various diseases due to their multipotent differentiation potential and immune regulatory activities. However, the lack of a clear understanding… read more here.
Keywords: heterogeneity; dissecting heterogeneity; reveals unique; human mscs ... See more keywords
Cryo-EM Reveals a Unique BRCA1 Complex in Metastasis
Sign Up to like & getrecommendations! Published in 2018 at "Microscopy and Microanalysis"
DOI: 10.1017/s143192761800658x
Abstract: Currently, there remains a critical need for mapping proteins implicated in the progression of cancer. Visualizing the biological complexes that support metastatic disease allows for a greater understanding of personalized and targeted therapies. The Breast… read more here.
Keywords: unique brca1; microscopy; brca1; cryo reveals ... See more keywords
Pressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity
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DOI: 10.1038/s41598-019-39261-8
Abstract: The prion protein (PrP) misfolds and assembles into a wide spectrum of self-propagating quaternary structures, designated PrPSc. These various PrP superstructures can be functionally different, conferring clinically distinctive symptomatology, neuropathology and infectious character to the… read more here.
Keywords: diversity; prion protein; reveals unique; prp ... See more keywords
The Characterization of Cardiac Explants Reveals Unique Fibrosis Patterns and a Predominance of CD8+ T Cell Subpopulations in Patients with Chronic Chagas Cardiomyopathy
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DOI: 10.3390/pathogens11121402
Abstract: Aim: The present study aimed to characterize the histopathological findings and the phenotype of inflammatory cells in the myocardial tissue of patients with end-stage heart failure (ESHF) secondary to CCC in comparison with ESHF secondary… read more here.
Keywords: characterization cardiac; reveals unique; chagas cardiomyopathy; explants reveals ... See more keywords