AZD9291 Resistance Reversal Activity of a pH‐Sensitive Nanocarrier Dual‐Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202002922
Abstract: Abstract AZD9291 can effectively prolong survival of non‐small cell lung cancer (NSCLC) patients. Unfortunately, the mechanism of its acquired drug resistance is largely unknown. This study shows that autophagy and fibroblast growth factor receptor 1… read more here.
Keywords: azd9291; resistance reversal; crgd; resistance ... See more keywords
Rare dimeric guaianes from Xylopia vielana and their multidrug resistance reversal activity.
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DOI: 10.1016/j.phytochem.2018.11.004
Abstract: Thirteen undescribed dimeric guaianes were isolated from the leaves of Xylopia vielana Pierre. Their structures were elucidated by NMR spectroscopy and mass spectrometry, and the absolute configurations of vielanins G-Q were determined by a combination… read more here.
Keywords: xylopia vielana; resistance reversal; spectroscopy; multidrug resistance ... See more keywords
Dihydro-β-agarofuran-Type Sesquiterpenoids from the Seeds of Celastrus virens and Their Multidrug Resistance Reversal Activity against the KB/VCR Cell Line.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c01182
Abstract: Twenty-nine dihydro-β-agarofuran-type sesquiterpenoids, including 17 new and 12 known compounds, were obtained from the seeds of Celastrus virens. The structures of the new isolates were characterized by spectroscopic methods and X-ray diffraction analysis. Among these,… read more here.
Keywords: reversal; agarofuran type; type sesquiterpenoids; dihydro agarofuran ... See more keywords