Thermodynamic Constraints Improve Metabolic Networks.
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DOI: 10.1016/j.bpj.2017.06.018
Abstract: In pursuit of establishing a realistic metabolic phenotypic space, the reversibility of reactions is thermodynamically constrained in modern metabolic networks. The reversibility constraints follow from heuristic thermodynamic poise approximations that take anticipated cellular metabolite concentration… read more here.
Keywords: reversibility constraints; reversibility; network; reconciliation ... See more keywords