Articles with "reversible p53" as a keyword



Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy

Sign Up to like & get
recommendations!
Published in 2017 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.201606230

Abstract: Cisplatin is a widely used chemotherapy drug, despite its significant ototoxic side effects. To date, the mechanism of cisplatin‐induced ototoxicity remains unclear, and hearing preservation during cisplatin‐based chemotherapy in patients is lacking. We found activation… read more here.

Keywords: cisplatin; efficacy; ototoxicity; cisplatin ototoxicity ... See more keywords