Articles with "reversible p53" as a keyword



Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy

Sign Up to like & get
recommendations!
Published in 2017 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.201606230

Abstract: Cisplatin is a widely used chemotherapy drug, despite its significant ototoxic side effects. To date, the mechanism of cisplatinā€induced ototoxicity remains unclear, and hearing preservation during cisplatinā€based chemotherapy in patients is lacking. We found activation… read more here.

Keywords: cisplatin; efficacy; ototoxicity; cisplatin ototoxicity ... See more keywords