Articles with "review preclinical" as a keyword



Microbiome contributions to pain: a review of the preclinical literature.

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Published in 2024 at "Pain"

DOI: 10.1097/j.pain.0000000000003376

Abstract: ABSTRACT Over the past 2 decades, the microbiome has received increasing attention for the role that it plays in health and disease. Historically, the gut microbiome was of particular interest to pain scientists studying nociplastic… read more here.

Keywords: pain; microbiome contributions; contributions pain; pain review ... See more keywords

New experimental therapies for glioblastoma: a review of preclinical research

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Published in 2025 at "Acta Neuropathologica Communications"

DOI: 10.1186/s40478-025-02105-w

Abstract: Glioblastoma is the most common and malignant glial tumor of the central nervous system with an incidence from 0.59 to 3.69 per 100 000 depending on the region. Patient prognosis remains poor, highlighting the urgent… read more here.

Keywords: glioblastoma review; therapies glioblastoma; research; new experimental ... See more keywords
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A Comprehensive Review on Preclinical Alzheimer's Disease Models: Evaluating their Clinical Relevance.

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Published in 2024 at "Current pharmaceutical biotechnology"

DOI: 10.2174/0113892010331845240802073645

Abstract: Alzheimer's disease (AD) is a neurological disorder that increases with age and must be treated immediately by worldwide healthcare systems. Internal neurofibrillary tau tangles and extracellular amyloid accumulation have been widely recognized as the primary… read more here.

Keywords: alzheimer disease; disease; comprehensive review; preclinical alzheimer ... See more keywords

Saffron nephroprotective effects against medications and toxins: A review of preclinical data

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Published in 2022 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2022.61344.13570

Abstract: Toxin and drug-induced nephrotoxicity (DIN) account for about 25% of all acute kidney injury cases and are associated with morbidity and increased utilization of healthcare services. No approved preventive compound is available for DIN. Saffron… read more here.

Keywords: medications toxins; review preclinical; saffron nephroprotective; effects medications ... See more keywords
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Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.592654

Abstract: Chalcones are among the leading bioactive flavonoids with a therapeutic potential implicated to an array of bioactivities investigated by a series of preclinical and clinical studies. In this article, different scientific databases were searched to… read more here.

Keywords: chalcones review; review preclinical; properties chalcones; pharmacological properties ... See more keywords