Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance
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DOI: 10.3390/molecules27072201
Abstract: Proteasome inhibitors have shown relevant clinical activity in several hematological malignancies, namely in multiple myeloma and mantle cell lymphoma, improving patient outcomes such as survival and quality of life, when compared with other therapies. However,… read more here.
Keywords: inhibitors molecular; proteasome inhibitors; development; mechanisms resistance ... See more keywords