UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00432
Abstract: Sulforaphane (SFN) is a potent anticancer agent which could protect the skin from ultraviolet (UV) radiation-induced insults. Currently, the metabolic rewiring and epigenetic reprograming induced by UVB and the role of SFN in UVB-mediated skin… read more here.
Keywords: uvb drives; sfn; epigenetic reprograming; metabolic rewiring ... See more keywords
Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2019.00081
Abstract: Leukemias driven by chromosomal translocation of the mixed-lineage leukemia gene (MLL or KMT2A) are highly prevalent in pediatric oncology. The poor survival rate and lack of an effective targeted therapy for patients with MLL-rearranged (MLL-r)… read more here.
Keywords: networks mll; leukemias epigenetic; epigenetic networks; rewiring epigenetic ... See more keywords