In silico discovery of small molecules that inhibit RfaH recruitment to RNA polymerase
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DOI: 10.1111/mmi.14093
Abstract: RfaH is required for virulence in several Gram‐negative pathogens including Escherichia coli and Klebsiella pneumoniae. Through direct interactions with RNA polymerase (RNAP) and ribosome, RfaH activates the expression of capsule, cell wall and pilus biosynthesis… read more here.
Keywords: discovery small; rfah recruitment; small molecules; rna polymerase ... See more keywords