Articles with "rfc pcna" as a keyword



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Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway

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Published in 2018 at "Nucleic Acids Research"

DOI: 10.1093/nar/gky943

Abstract: Abstract DNA-damage tolerance protects cells via at least two sub-pathways regulated by proliferating cell nuclear antigen (PCNA) ubiquitination in eukaryotes: translesion DNA synthesis (TLS) and template switching (TS), which are stimulated by mono- and polyubiquitination,… read more here.

Keywords: hltf; damage tolerance; polyubiquitination; choice ... See more keywords