Effect of RNA sequence context and stereochemistry on G-quadruplex-RHAU53 interaction.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.09.045
Abstract: RNA G-quadruplex (rG4) structure and its association with rG4-binding proteins/peptides are important for its function. However, there is very limited study that investigates what factors are involved in rG4 that drive the rG4-protein/peptide interaction. Here… read more here.
Keywords: rg4; rna sequence; rhau53; effect rna ... See more keywords
QUADRatlas: the RNA G-quadruplex and RG4-binding proteins database
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac782
Abstract: Abstract RNA G-quadruplexes (RG4s) are non-canonical, disease-associated post-transcriptional regulators of gene expression whose functions are driven by RNA-binding proteins (RBPs). Being able to explore transcriptome-wide RG4 formation and interaction with RBPs is thus paramount to… read more here.
Keywords: rg4; quadruplex rg4; rna quadruplex; rg4s ... See more keywords
G4Atlas: a comprehensive transcriptome-wide G-quadruplex database
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac896
Abstract: Abstract RNA G-quadruplex (rG4) is a vital RNA tertiary structure motif that involves the base pairs on both Hoogsteen and Watson-Crick faces of guanines. rG4 is of great importance in the post-transcriptional regulation of gene… read more here.
Keywords: rg4; database; transcriptome wide; quadruplex database ... See more keywords
Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky861
Abstract: Abstract RNA G-quadruplexes (rG4s) are secondary structures in mRNAs known to influence RNA post-transcriptional mechanisms thereby impacting neurodegenerative disease and cancer. A detailed knowledge of rG4–protein interactions is vital to understand rG4 function. Herein, we… read more here.
Keywords: nras rna; rg4; gar domain; quadruplex ... See more keywords
RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria
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DOI: 10.1128/mbio.02926-19
Abstract: G-quadruplex in RNA (rG4) mediates various biological functions and cellular processes in eukaryotic organisms. However, the presence, locations, and functions of rG4 are still elusive in prokaryotes. Here, we found that rG4 is an abundant… read more here.
Keywords: range bacterial; gene regulation; bacterial species; rg4 ... See more keywords
Inhibitory Activities of Rare Ginsenoside Rg4 on Cecal Ligation and Puncture-Induced Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810836
Abstract: Sepsis is an uncontrolled response to inflammatory infection and is associated with high levels of mortality and morbidity. Rg4 is a rare ginsenoside mainly found in the leaves of Panax ginseng C. A. Meyer and… read more here.
Keywords: sepsis; clp; rg4; group ... See more keywords
Ginsenoside Rg4 enhances the inductive effects of human dermal papilla spheres on hair growth via the AKT/GSK-3β/β-catenin signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.2101.01032
Abstract: Ginsenoside Rg4 is a rare ginsenoside that is naturally found in ginseng, and exhibits a wide range of biological activities, including antioxidant and anti-inflammatory properties, in several cell types. The purpose of this study was… read more here.
Keywords: rg4; catenin signaling; catenin; signaling pathway ... See more keywords